Search results for "pair [nucleon]"
showing 10 items of 68 documents
Expression of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents.
1997
Abasic sites represent ubiquitous DNA lesions that arise spontaneously or are induced by DNA-damaging agents. They block DNA replication and are considered to be cytotoxic and mutagenic. The key enzymes involved in the repair of abasic sites are apurinic/apyrimidinic (AP) endonucleases which process these lesions in an error-free mechanism. To analyze the role of AP endonuclease in the protection of mammalian cells against DNA damaging agents, we have transfected both the human (APE) and the yeast (APN1) AP endonuclease in Chinese hamster cells and compared the effects of expression of these genes in stable transfectants as to survival of cells and formation of chromosomal aberrations. Alth…
A NOTE ON THE CATEGORICAL NOTIONS OF NORMAL SUBOBJECT AND OF EQUIVALENCE CLASS
2021
In a non-pointed category E, a subobject which is normal to an equivalence relation is not necessarily an equivalence class. We elaborate this categorical distinction, with a special attention to the Mal'tsev context. Moreover, we introduce the notion of fibrant equipment, and we use it to establish some conditions ensuring the uniqueness of an equivalence relation to which a given subobject is normal, and to give a description of such a relation.
On fixed points of alpha-eta-psi-contractive multifunctions
2014
Recently Samet et al. [B. Samet, C. Vetro, P. Vetro, Fixed point theorem for alpha-psi-contractive type mappings, Nonlinear Anal., 75 (2012), 2154{2165] introduced the notion of alpha-psi-contractive type mappings and established some fixed point theorems in complete metric spaces. Succesively, Asl et al. [J.H. Asl, SH. Rezapour, N. Shahzad, On fixed point of alpha-contractive multifunctions, Fixed Point Theory Appl., 2012, 212 (2012)] introduced the notion of alpha_*-psi-contractive multifunctions and give a fixed point result for these multifunctions. In this paper we obtain certain new fixed point and common fixed point theorems via alpha_*-admissible multifuncions with respect to eta. T…
Nano into Micro Formulations of Tobramycin for the Treatment of Pseudomonas aeruginosa Infections in Cystic Fibrosis.
2017
Here, nano into micro formulations (NiMs) of tobramycin for the treatment of Pseudomonas aeruginosa airway infections in cystic fibrosis (CF) are described. NiMs were produced by spray drying a solution containing polymers or sugars and a nanometric polyanion–tobramcyin complex (PTC), able to achieve a prolonged antibiotic release. NiMs properties were compared to TOBIPodhaler(Novartis), the only one commercially available dry powder inhalatory formulation based on porous microparticles. Produced NiMs showed adequate characteristics for pulmonary administration, as spherical shape, micrometric size, and high cytocompatibility toward human bronchial epithelial cells. Contrarily to TOBIPodhal…
Electroweak measurements in electron-positron collisions at W-boson-pair energies at LEP
2013
The ALEPH, DELPHI, L3, OPAL collaborations and LEP Electroweak Working Group.-- arXiv:1302.3415
Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma.
2008
Uveal melanoma is associated with a high mortality rate once metastases occur, with over >90% of metastatic patients dying within less than 1 year from metastases to the liver. The intraarterial hepatic (iah) administration of the alkylating agent fotemustine holds some promise with response rates of 36% and median survival of 15 months. Here, we investigated whether the DNA-repair-protein MGMT may be involved in the variability of response to fotemustine and temozolomide in uveal melanoma. Epigenetic inactivation of MGMT has been demonstrated to be a predictive marker for benefit from alkylating agent therapy in glioblastoma. We found a methylated MGMT promoter in 6% of liver metastases fr…
Ion pair complexes and anion binding in the solution of a ditopic receptor.
2016
The synthesis and crystal structures with alkali halides of a ditopic benzo-15-crown-5 bis-urea receptor have been presented. In addition, the anion binding properties of and its alkali metal complexes in solution are presented. A comprehensive single-crystal X-ray crystallographic study of , all together 13 crystal structures, including the ion pair complexes with NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbF, RbCl, and RbI, give a detailed view of how behaves in the solid-state with different alkali halides depending on the size of the cation and anion. In the solid-state forms a 1 : 1 complex with a sodium cation and the anion is complexed as a contact (NaCl) or a separate ion pair (NaBr, NaI).…
Measurements of the top quark branching ratios into channels with leptons and quarks with the ATLAS detector
2015
Measurements of the branching ratios of top quark decays into leptons and jets using events with t[bar over t] (top antitop) pairs are reported. Events were recorded with the ATLAS detector at the LHC in pp collisions at a center-of-mass energy of 7 TeV. The collected data sample corresponds to an integrated luminosity of 4.6 fb[superscript −1]. The measured top quark branching ratios agree with the Standard Model predictions within the measurement uncertainties of a few percent.
Advanced spatio-temporal point processes for the Sicily seismicity analysis
2018
Due to the complexity of the generator process of seismic events, we study under several aspects the interaction structure between earthquake events using recently developed spatio-temporal statistical techniques and models. Using these advanced statistical tools, we aim to characterise the global and local scale cluster behaviour of the Easter Sicily seismicity considering the catalogue data since 2006, when the Italian National Seismic Network was upgraded and earthquake location was sensibly improved. Firstly, we characterise the global complex spatiotemporal interaction structure with the space-time ETAS model where background seismicity is estimated non-parametrically, while triggered …
Coincidence and common fixed points of weakly reciprocally continuous and compatible hybrid mappings via an implicit relation and an application
2015
Using the hybrid version of the notion of weakly reciprocal continuous mappings due to Gairola et al. [Coincidence and fixed point for weakly reciprocally continuous single-valued and multi-valued maps, Demonstratio Math. (2013/2014), accepted], we prove a coincidence and common fixed point theorem for a hybrid pair of compatible mappings via an implicit relation. Our main result improves and generalizes a host of previously known theorems. As an application, we give a homotopy theorem which supports our main result.